Juniper Publishers Journal of Dairy and Veterinary Sciences

Journal of Dairy & Veterinary Sciences - Juniper Publishers   Introduction Healthy udder of milking cows is one of the most important factors of successful breeding from the health as well as economic point of view. Mastitis is defined as an inflammation of the parenchyma of mammary gland, which not only reduces milk yield but alters milk composition [ 1 ] also. It is one of the most problematic diseases and continues to have a major economic impact on the dairy industry throughout the world [ 2 ]. It is a devastating disease haunting the dairy industry leading to reservoir of infection for human beings and the economic losses due to high morbidity, discarded milk, reduced milk production and increased antimicrobial resistance of the organisms in animals treated with antibiotics [ 3 ]. The genome sequences of many of the major mastitis causing pathogens are now available and can be utilized to develop nucleic acid-based test...

Journal of Dairy & Veterinary Sciences - Juniper Publishers   Introduction The spread of mastitis pathogens causes large economic losses to the dairy industry. These losses include increased involuntary culling rate, reduced milk production, increase domatic cell count, and discarded milk [ 1 , 2 ]. Costs associated with mastitis infections in the U.S. dairy industry have been estimated at nearly US $2 billion per year [ 3 ]. Streptococcus uberis is one of the most common gram-positive causes of clinical mastitis and contributes to a large proportion of subclinical mastitis cases [ 4 , 5 ]. Streptococcus uberis infections are often difficult to cure with traditional intra-mammary antibiotic preparations, especially in older animals [ 6 , 7 ]. Similar to treatment trials focused on Staphylococcus aureus ( S. aureus ) intra-mammary infection, increased somatic cell counts before treatment was associated with a decreased probability o...